Pericardial disease is often under recognized and difficult to diagnose. Heart specialists at Mayo Clinic discuss their multi-disciplinary approach to optimal management of pericarditis, including their pioneering approach to noninvasive diagnostic imaging. Jae K. Oh, M.D., Mayo Clinic cardiologist, reviews the keys to diagnosing pericarditis using echocardiography. Leslie T. Cooper, M.D., Mayo Clinic cardiologist, outlines the medical management for pericarditis. Kevin L. Greason, M.D., Mayo Clinic cardiac surgeon, details the Mayo Clinic surgical approach to management of pericarditis with the pericardiectomy procedure. Mayo Clinic cardiac surgeon, Kevin Landolfo, M.D., discusses surgical outcomes following pericardiectomy.