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A commonly used erectile dysfunction drug, sildenafil, doesn't help patients who have heart failure with preserved ejection fraction, a condition in which the heart's lower chambers are stiff and cannot relax and fill fully between beats.
The Center for Regenerative Medicine at Mayo Clinic investigates what advances of stem cell biology would be useful to apply in the treatment of patients with end stage diseases.
S. Vincent Rajkumar, M.D., Mayo Clinic hematologist, discusses the first systematic study to determine association of monoclonal gammopathy of undetermined significance (MGUS) with all diseases in 17,398 patients, published in Mayo Clinic Proceedings.
Rajiv Gulati, M.D., Ph.D., and Bruce D. Johnson, Ph.D., discuss insights that Dr. Johnson's team of researchers gleaned during their trek to Mount Everest.
Rajiv Gulati, M.D., Ph.D., and Sharonne N. Hayes, M.D., discuss how a research study was initiated by patients via social media to study spontaneous coronary artery dissection (SCAD).
Dr. Douglas Wood, consultant in cardiovascular diseases and the Center for Innovation at Mayo Clinic in Rochester, MN, discusses his article on using design research in the community for health reform.