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How a year's worth of experience of pulsed field ablation for AFib has revolutionized my practice

In this episode of the Mayo Clinic CV CME podcast series, host Anthony H. Kashou, M.D., assistant professor of medicine and advanced cardiology fellow, and Christopher V. DeSimone, M.D., Ph.D., and Abhishek J. Deshmukh, M.B.B.S., cardiac electrophysiologists, explore how pulsed field ablation (PFA) has reshaped the treatment of atrial fibrillation (AFib) and changed clinical practice in electrophysiology. Unlike traditional thermo- or cryo-based approaches, PFA uses high-voltage electrical pulses to provide a relatively nonthermal ablation approach, which is more selective for cardiac tissue. It offers an improved safety profile for ablation and a more efficient procedure, leading to shorter times under anesthesia. Well after one year of integrating this procedure into practice, and over 1,000 cases, Drs. DeSimone and Deshmukh discuss the advantages for patients and for practicing electrophysiologists.

 

For more information or to refer a patient, visit Mayo Clinic Medical Professionals — Cardiovascular Diseases.

 

 

 


Published

July 16, 2025

Created by

Mayo Clinic