Modern treatment for polycystic kidney disease

Mikel Prieto, M.D., a transplant surgeon at Mayo Clinic's campus in Rochester, Minnesota, discusses a landmark case that set a new standard of care for patients with polycystic kidney disease.

Polycystic kidney disease is an inherited disorder in which clusters of cysts develop primarily in the kidneys. When severe, polycystic kidney disease causes kidney failure. Patients with polycystic kidney disease who require kidney transplant have traditionally been treated with two separate surgeries: one to receive a kidney transplant and the other to remove the diseased kidneys.

Mayo Clinic specialists use a modern, minimally invasive surgical technique that combines living-donor transplant and bilateral nephrectomy into one operation. Learn how this approach helps patients avoid dialysis and the risks associated with two separate surgeries and recover more quickly.

Video content outline:

  • Introduction
  • Rationale and specifics of combined living-donor transplant and bilateral nephrectomy (0:29)
  • Polycystic kidney disease as a genetic disease (1:04)
  • Polycystic kidney disease symptoms and diagnosis (1:21)
  • Jolinda's landmark case (1:55)
  • Risks of treating polycystic kidney disease with two surgeries (3:28)
  • Living-donor transplantation (4:08)
  • Kidney paired donation (4:40)
  • Long-term outlook (4:53)


January 18, 2017

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Mayo Clinic