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ADYR A. MOSS: Living donor liver transplantation matters because we live in a crisis. There is a pervasive organ shortage. There are areas in the country where organs are less available than other areas of the country. So living donor liver transplantation is just one modality that the transplant community is using in order to improve access to liver transplantation to some patients. The benefit of living donor liver transplantation is in improving quality of life and decreasing mortality for the recipient.

Mayo Clinic has been a pioneer in the treatment of unresectable chloangiocarcinomas, particularly the ones that happen in the background of primary sclerosing cholangitis. The therapy involves a very intensive multimodality neoadjuvant therapy. And if those patients continue to do well following that therapy, they may become eligible for liver transplantation. And those patients even further can be eligible for living donor transplants.

So that way, we are offering a state-of-the-art therapy for the unresectable tumors that some programs may not offer. And in addition to that, we're offering living donor transplantation, which, again, increases the access to transplant for those patients. And Mayo Clinic also offers adult left and right living donor liver transplants, depending, of course, on the recipient and donor anatomy.

At the Mayo Clinic, following patients' liver transplant, they usually are cared by our multidisciplinary team for several weeks post-transplant. And our goal is always to send the patients back to their referring physicians, so they can continue the care, wherever they're coming from.

Improving access with living-donor liver transplantation

Adyr A. Moss, M.D., chair of Transplant Surgery at Mayo Clinic's campus in Phoenix/Scottsdale, Arizona, discusses the benefits of living-donor liver transplantation, which can improve quality of life and decrease mortality for the recipient. Dr. Moss highlights therapies available for specialized cases, including unresectable cholangiocarcinomas.


Published

October 13, 2016

Created by

Mayo Clinic